Organic nitroso compounds
eMolecules Pharmablock / tert-butyl 2-phenylpiperazine-1-carboxylate / 25mg / 788479716 / PB07807 / 0.000 / 886766-60-5 / MFCD07367734 / 262.353 / C15H22N2O2
Pharmablock / tert-butyl 2-phenylpiperazine-1-carboxylate / 25mg / 788479716 / PB07807 / 0.000 / 886766-60-5 / MFCD07367734 / 262.353 / C15H22N2O2
Cayman Chemical N-NItroso-N-methylnIlIn 25mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Cayman Chemical N-NItroso Atenolol 10mg
A genotoxic derivative of (±)-atenolol; induces DNA fragmentation in rat hepatocytes from 0.1 to 1 mM
Cayman Chemical N-NItroso-N-methylnIlIn 50mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Cayman Chemical N-NItroso SarcosIn-d3 5mg
An internal standard for the quantification of nitroso sarcosine by GC- or LC-MS
Medchemexpress LLC N-nitroso-n-methyl-4-aminobutyric acid | 61445-55-4 | MFCD00869939 | 99.9% | 146.14 | C5H10N2O3 | 50 MG
N-nitroso-n-methyl-4-aminobutyric acid is a tobacco-derived nitrosamine used as a research chemical and analytical reference. It is supplied as a colorless to light yellow liquid with high reported purity and is intended for research use only.
- High purity (HPLC): 99.88%.
- Molecular formula C5H10N2O3.
- Molecular weight 146.14.
- Appearance liquid, colorless to light yellow.
- Available in small milligram packs, including 50 mg.
- CAS number 61445-55-4.
- Tobacco-specific nitrosamine; identified as a carcinogen.
- For research use only; not for sale to patients.
Medchemexpress LLC Nitrosobenzene | 586-96-9 | >98.0% | 1 G
Nitrosobenzene (C6H5NO) is an organic nitroso compound used as a reagent and intermediate in organic synthesis and biochemical research. It functions as a radical scavenger and is used to study oxidative DNA damage and neutrophil respiratory burst reactions.
- High purity (>98.0%) reagent grade suitable for research applications.
- Molecular weight 107.11 g/mol and formula C6H5NO.
- Commonly used as an intermediate for azoxybenzene and azobenzene synthesis.
- Useful as a radical scavenger in assays of oxidative DNA damage.
- Supplied as a 1 G solid for laboratory use; follow SDS for handling and safety.
Cayman Chemical N-NItroso SarcosIn 100mg
A carcinogen; induces the formation of metastatic liver carcinomas in mice at 225 mg/kg
![Medchemexpress LLC N-nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | 144.21 g/mol | C7H8D4N2O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222594.png-250.jpg)
Medchemexpress LLC N-nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | 144.21 g/mol | C7H8D4N2O | 5 MG
N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium-labeled isotopologue of N-nitroso-3-azabicyclo[3.3.0]octane provided as a reference material for analytical and research applications. It is supplied as a solid for use as an internal standard in mass spectrometry and isotopic labeling studies; not for human or veterinary use.
- Deuterium-labeled internal standard for mass spectrometry.
- Suitable for quantitative and qualitative analytical methods.
- Provided with batch-specific certificate of analysis.
- Stable solid form suitable for recommended long-term storage.
- Intended for research use only.
Medchemexpress LLC N-nitrosomorpholine-d8 | 1219805-76-1 | MFCD08704880 | 99.7% | 124.17 g·mol⁻1 | C4D8N2O2 | 5 MG
N-Nitrosomorpholine-d8 is a deuterium-labeled analogue of N-nitrosomorpholine used as an isotope-labeled reference standard and internal standard for analytical testing and quantitation of nitrosamines. It is photosensitive and a potent animal carcinogen; handle with appropriate engineering controls and personal protective equipment, and consult the SDS and batch COA for safety and purity details.
- CAS number: 1219805-76-1.
- Molecular formula: C4D8N2O2.
- Molecular weight: 124.17 g·mol⁻1.
- Purity (HPLC): 99.7%.
- Appearance: Colorless to light yellow liquid.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended use: isotope-labeled reference standard for analytical and quantitation applications.
Medchemexpress LLC (R)-PR-924 | 98.5% | 618.72 | 10 MG
(R)-PR-924 is an isomer of PR-924 used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor that covalently modifies proteasomal N-terminal threonine active sites. It inhibits growth and triggers apoptosis in multiple myeloma cells, demonstrating antitumor activities.
- Used as an experimental control
- Inhibits growth and triggers apoptosis in multiple myeloma cells
- Covalently modifies proteasomal N-terminal threonine active sites
- Acts as a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor
- Demonstrates antitumor activities
Medchemexpress LLC N-Nitrosomorpholine | 59-89-2 | 100.0% | 1 ML
N-Nitrosomorpholine is a photosensitive nitrosamine that is carcinogenic and can be used to construct animal cancer models. It is for research use only and not sold to patients. High doses of N-Nitrosomorpholine can cause significant cytoplasmic and nuclear changes in livers, leading to toxic damage, single-cell necrosis, loss of glycogen, and induction of giant cell production, bile duct proliferation, and fibrosis. Cirrhosis becomes obvious by the 4th week of treatment, worsening by weeks 15-20, and leading to metastatic liver cancer and death in animals by weeks 30-40.
- Photosensitive nitrosamine
- Carcinogenic agent
- Used for animal cancer model construction
- For research use only
- Induces liver toxicity and cellular changes
- Causes necrosis and fibrosis in liver tissue
- Can lead to metastatic liver cancer and mortality in animals
Medchemexpress LLC (R)-PR-924 | 1416709-79-9 | 98.5% | 618.72 | 50 MG
(R)-PR-924 is an isomer of PR-924, which can be used as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC50 of 22 nM. It covalently modifies proteasomal N-terminal threonine active sites, inhibits growth, and triggers apoptosis in multiple myeloma (MM) cells, also exhibiting antitumor activities.
- Selective immunoproteasome subunit LMP-7 inhibitor.
- Covalently modifies proteasomal N-terminal threonine active sites.
- Inhibits growth in multiple myeloma (MM) cells.
- Triggers apoptosis in multiple myeloma (MM) cells.
- Exhibits antitumor activities.
- Can be used as an experimental control.
Medchemexpress LLC (R)-PR-924 | 98.5% | 618.72 | 25 MG
(R)-PR-924 is an isomer of PR-924 (HY-123587) and serves as an experimental control. PR-924 is a selective tripeptide epoxyketone immunoproteasome subunit LMP-7 inhibitor with an IC50 of 22 nM. It covalently modifies proteasomal N-terminal threonine active sites, inhibits growth, and triggers apoptosis in multiple myeloma (MM) cells, exhibiting antitumor activities.
- Serves as an experimental control
- Inhibits growth in multiple myeloma (MM) cells
- Triggers apoptosis in multiple myeloma (MM) cells
- Exhibits antitumor activities
- Covalently modifies proteasomal N-terminal threonine active sites
- Selective immunoproteasome subunit LMP-7 inhibitor
- IC50 of 22 nM for LMP-7 inhibition